The World Health Organization's (WHO) 2025 technical brief, supported by research contributions from multiple institutions, provides a comprehensive account of the criteria for identifying infants and young children with moderate wasting who should receive specially formulated foods (SFFs).
The document begins by emphasizing the need for a targeted approach to supplementation, as universal provision risks displacing breastfeeding and home diets, imposes financial burdens, and may undermine programme scalability.
Individual risk factors include:
In high-risk contexts, including humanitarian crises, widespread food insecurity, poor water and sanitation conditions, low socioeconomic status, or high seasonal prevalence of wasting, WHO advises that all moderately wasted children be considered for SFFs.
The Guideline Development Group reviewed randomized controlled trials comparing SFFs with counselling alone and judged the benefits of SFFs to be moderate, with moderate certainty.
WHO recommends:
The document emphasizes the importance of shaping implementation by local feasibility, acceptability, and equity considerations.
